Imaging of Human Insulin Secreting Cells with Gd-DOTA-P88, a Paramagnetic Contrast Agent Targeting the Beta Cell Biomarker FXYD2γa
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منابع مشابه
Safety of Gadoterate Meglumine (Gd-DOTA) as a Contrast Agent for Magnetic Resonance Imaging
BACKGROUND Safety is a primary concern with contrast agents used for MRI. If precautions could be taken before the repeated administration of gadolinium-based contrast media, then the awareness and management of adverse reactions would be more efficient. OBJECTIVES To assess the safety and efficacy of gadoterate meglumine (Gd-DOTA) [Magnescope® in Japan, Dotarem® in other countries], a gadoli...
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Nanoparticles are unique that enable many promising medical and technological applications intheir physical, and chemical properties. It is widely accepted that nanoparticles should bethoroughly tested for health nanotoxicity, but a moderate risk analysis is currently prevented by arevealing absence of mechanistic knowledge of nanoparticle toxicity. The purpose of this study<b...
متن کاملThe Assessment of Toxicity Characteristics of Cellular Uptake of Paramagnetic Nanoparticles as a New Magnetic Resonance Imaging Contrast Agent
Nanoparticles are unique that enable many promising medical and technological applications intheir physical, and chemical properties. It is widely accepted that nanoparticles should bethoroughly tested for health nanotoxicity, but a moderate risk analysis is currently prevented by arevealing absence of mechanistic knowledge of nanoparticle toxicity. The purpose of this study<b...
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Background: Glucose transporter (Glut), a cellular transmembrane receptor, has a key role in the metabolism of cell glucose and is also associated with various human carcinomas.Objective: In this study, we evaluated a magnetic resonance (MR) imaging contrast agent for tumor detection based on paramagnetic gadolinium oxide (Gd2O3) coated polycyclodextrin (PCD) and mod...
متن کاملdifferentiation of human embryonic stem cells into insulin- secreting cells
introduction: type i diabetes mellitus is caused by autoimmune destruction of the insulin-producing β-cells. a new potential method for curing the disease is transplantation of differentiated insulin- secreting cells from human embryonic stem cells. methods: human embryonic stem cell lines (royan h1) were used to produce embryoid bodies. differentiation carried out by growth factor-mediated sel...
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ژورنال
عنوان ژورنال: Molecules
سال: 2018
ISSN: 1420-3049
DOI: 10.3390/molecules23092100